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Prof. Dr. Katrin Marcus

Professor , Medizinisches Proteom Center, The Ruhr-Universität Bochum

Associated Professorship

Functional Proteomics

Research and Practice projects (selection)

Publications (selection)

1. Autophagy inhibition promotes alpha-synuclein release and transfer via extracellular vesicles with a hybrid autophago/exosome-like phenotype, Minakaki G, Menges S, Kittel A, Emmanouilidou E, Schaeffner I, Barkovits K, Bergmann A, Rockenstein E, Adame A, Marxreiter F, Mollenhauer B, Galasko D, Irén Buzá E, Schlötzer-Schrehardt U, Marcus K, Xiang W, Chichung Lie D, Vekrellis K, Masliah E, Winkler J, Klucken J., Autophagy 2018, 14(1):98-119

2. Distinct metabolomic signature in cerebrospinal fluid in early parkinson's disease, Trezzi JP, Galozzi S, Jaeger C, Barkovits K, Brockmann K, Maetzler W, Berg D, Marcus K, Betsou F, Hiller K, Mollenhauer B (2017), Mov Disord., 32(10):1401-1408 

3. Proteomics of rimmed vacuoles define new risk allele in inclusion body myositis.,  Güttsches AK, Brady S, Krause K, Maerkens A, Uszkoret J, Eisenacher M, Schreiner A, Galozzi S, Mertens-Rill J, Tegenthoff M, Holton JL, Harms MB, Lloyd, TE, Vorgerd M, Weihl CC*, Kley R*, Marcus K* (2017) Annals Neurol, 81(2):227-239 

4. Proteomic characterization of neuromelanin granules isolated from human substantia nigra by laser-microdissection, Plum S, Steinbach S, Attems J, Keers S, Riederer P, Gerlach M, May C, Marcus K (2016) Sci Rep., 6:37139.

5. Mutant desmin substantially perturbs mitochondrial morphology, function and maintenance in skeletal muscle tissue, Winter L, Wittig I, Peeva, V, Eggers B, Heidler J, Chessevier F, Kley RA, Barkovits K, Strecker V, Berwanger C, Herrmann H, Marcus K, Kornblum C, Kunz WS, Schröder R, Clemen CS (2016) Acta Neuropathol, 132(3):453-73

5. A combined laser microdissection and mass spectrometry approach reveals new disease relevant proteins accumulating in aggregates of filaminopathy patients, Kley R.A. , Maerkens A., Leber Y., Theis V., Schreiner A., van der Ven P.F.M., Uszkoreit J., Stephan C., Eulitz S., Euler N., Kirschner J., Müller K., Meyer H.E., Tegenthoff M., Fürst D.O., Vorgerd M., Müller T., Marcus K., Mol Cell Proteomics, 12(1), 215-227

6. Differential proteomic analysis of abnormal intramyoplasmic aggregates in desminopathy, Maerkens A, Kley RA, Olivé M, Theis V, van der Ven PF, Reimann J, Milting H, Schreiner A, Uszkoreit J, Eisenacher M, Barkovits K, Güttsches AK, Tonillo J, Kuhlmann K, Meyer HE, Schröder R, Tegenthoff M, Fürst DO, Müller T, Goldfarb LG, Vorgerd M, Marcus K, J Proteomics 2013, 90, 14-27 

7. Genetic analysis of the mouse brain proteome, Klose J., Nock C., Herrmann M.,. Stuhler K., Marcus K., Bluggel M., Krause E., Schalkwyk L.C., Rastan S., Brown S.D., Bussow K., Himmelbauer H., Lehrach H. , Nat. Genet., 2002 (30(4)), 385-393.

Casegroup

Medicine and Health